The Foundation for the National Institutes of Health (FNIH) has selected Jeannie T. Lee, M.D., Ph.D., as the 2016 winner of the Lurie Prize in Biomedical Sciences for uncovering the functions of long, noncoding RNA (lncRNA) in epigenetic regulation. Her work has accelerated the understanding of mechanisms driving epigenetic regulation, which involves changes in gene function without changing the DNA sequence.
Dr. Lee is a Professor of Genetics and Pathology at Harvard Medical School and at Massachusetts General Hospital and a Howard Hughes Medical Institute Investigator. Dr. Lee uses the X chromosome as her model of choice, where she investigates how the inactivation of this chromosome could be used to treat congenital diseases such as Rett, CDKL5 and Fragile X Syndromes and numerous cancers such as breast, ovarian, blood, intestinal and male germ cell tumors where there is often an extra x-chromosomal copy.
The Lurie Prize will be presented to Dr. Lee on May 18, 2016 at the House of Sweden in Washington, D.C.
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"I hope that we will one day be able to translate these discoveries into treatment for a multitude of diseases.”
—Dr. Jeannie T. Lee